Book Hotels in Upstate South Carolina, SC

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Top Upstate South Carolina hotels

Cambria Hotel Greenville

Cambria Hotel Greenville

3 out of 5
135 Carolina Point Parkway, Greenville, SC
Fully refundableReserve now, pay when you stay
$144 nightly
The price is $158 total per night from Jun 15 to Jun 16
$158 total
Jun 15 - Jun 16
Total includes taxes and fees
This hotel features a restaurant, a gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy ...
"The room was good but the bathroom was a little bit dirty like just bad cleaner. And the other thing was the room was hot all night even when i putted the Ac at 65 degrees"

Reviewed on Jun 2, 2025

Cambria Hotel Greenville
Best Western Plus Greenville I-385 Inn & Suites

Best Western Plus Greenville I-385 Inn & Suites

2.5 out of 5
831 Congaree Rd, Greenville, SC
Fully refundableReserve now, pay when you stay
$88 nightly
The price is $97 total per night from Jun 22 to Jun 23
$97 total
Jun 22 - Jun 23
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Guests will ...
"The breakfast was amazing. Staff very friendly. The room was very clean."

Reviewed on Jun 2, 2025

Best Western Plus Greenville I-385 Inn & Suites
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St, Greenville, SC
Fully refundableReserve now, pay when you stay
$131 nightly
The price is $144 total per night from Jun 30 to Jul 1
$144 total
Jun 30 - Jul 1
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 24-hour business center, free WiFi in public ...
"Large hotel with a beautiful lobby. Overnight parking is very reasonable. The pool was quiet and nice. The “mini fridge” in the room aren’t actually fridges though. They are “coolers” and not meant to keep medicine or food cold. So that’s something to keep in mind if you like having milk or ..."

Reviewed on Jun 3, 2025

Hyatt Regency Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd, Greenville, SC
Fully refundable
$107 nightly
The price is $118 total per night from Jun 29 to Jun 30
$118 total
Jun 29 - Jun 30
Total includes taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
"Great place to stay. Very convenient to downtown Greenville. Our room was very clean and comfortable. Beautiful hotel and pleasant, helpful staff. Thoroughly enjoyed our stay."

Reviewed on Jun 2, 2025

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$109 nightly
The price is $119 total per night from Jul 4 to Jul 5
$119 total
Jul 4 - Jul 5
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
"Sure was nice"

Reviewed on May 26, 2025

Hilton Greenville
Comfort Inn Greenville - Haywood Mall

Comfort Inn Greenville - Haywood Mall

2.5 out of 5
246 Congaree Road, Greenville, SC
Fully refundableReserve now, pay when you stay
$91 nightly
The price is $99 total per night from Jun 8 to Jun 9
$99 total
Jun 8 - Jun 9
Total includes taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
"The gazebo siiting area & the office entryway were very nice. Entryway had nice floral & fountain arrangement. Our bathroom had a sewer smell which we reported at check out & management was going to get maintenance right on it."

Reviewed on Jun 1, 2025

Comfort Inn Greenville - Haywood Mall
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$97 nightly
The price is $107 total per night from Jun 28 to Jun 29
$107 total
Jun 28 - Jun 29
Total includes taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
"The reakfast area coulsnt keep up. The hallways smelled like wet dog. Rooms were clean."

Reviewed on Jun 2, 2025

Hyatt Place Greenville/Haywood
La Quinta Inn & Suites by Wyndham Greenville Haywood

La Quinta Inn & Suites by Wyndham Greenville Haywood

3 out of 5
65 W Orchard Park Dr, Greenville, SC
Fully refundableReserve now, pay when you stay
$71 nightly
The price is $78 total per night from Jun 14 to Jun 15
$78 total
Jun 14 - Jun 15
Total includes taxes and fees
This hotel features a gym and a seasonal outdoor pool. There's no skimping on freebies - guests receive free full breakfast, free WiFi, and free self parking. ...
"Clean. The receptionist is very nice Breakfast was good!"

Reviewed on Jun 2, 2025

La Quinta Inn & Suites by Wyndham Greenville Haywood
Days Inn by Wyndham Anderson

Days Inn by Wyndham Anderson

2 out of 5
1007 George Smith Mill Rd, Anderson, SC
Fully refundableReserve now, pay when you stay
$59 nightly
The price is $65 total per night from Jun 8 to Jun 9
$65 total
Jun 8 - Jun 9
Total includes taxes and fees
This motel doesn't skimp on freebies - guests receive free continental breakfast, free WiFi, and free self parking. Business travelers can take advantage of ...
"Fabulous, clean, quiet, convenient i can go on and on. The quality of the stay was wonderful and staff were ao hospitable and accommodating. Will recommend 10/10"

Reviewed on Jun 2, 2025

Days Inn by Wyndham Anderson
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Upstate South Carolina hotels

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

128 Interstate Blvd, Anderson, SC
$72 nightly
The price is $80 total per night from Jun 10 to Jun 11
$80 total
Jun 10 - Jun 11
Total includes taxes and fees
6.8/10 (789 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Upstate South Carolina hotel reviews by fellow wanderers

Hyatt Regency Greenville

Hyatt Regency Greenville

5 out of 5
Posted 1 day ago
Travelocity Verified Review
"Large hotel with a beautiful lobby. Overnight parking is very reasonable. The pool was quiet and nice. The “mini fridge” in the room aren’t actually fridges though. They are “coolers” and not meant to keep medicine or food cold. So that’s something to keep in mind if you like having milk or leftovers. "
A verified traveler stayed at Hyatt Regency Greenville
Hyatt Regency Greenville
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