Book Hotels in Upstate South Carolina, SC

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Top Upstate South Carolina hotels

Hotel Hartness

Hotel Hartness

4 out of 5
120 Halston Avenue Greenville SC
$209 nightly
The price is $230 total per night from Apr 26 to Apr 27
$230 total
Apr 26 - Apr 27
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Enjoy the seasonal outdoor pool and perks like free self parking. ...
Always a great time at Hotel Hartness with service, cleanliness and attention to detail. The grounds are exceptional as well

Reviewed on Apr 6, 2026

Opens in a new windowHotel Hartness
Grand Bohemian Lodge Greenville, Autograph Collection

Grand Bohemian Lodge Greenville, Autograph Collection

4 out of 5
44 EAST CAMPERDOWN WAY Greenville SC
Fully refundableReserve now, pay when you stay
$306 nightly
The price is $336 total per night from Apr 27 to Apr 28
$336 total
Apr 27 - Apr 28
Total with taxes and fees
A full-service spa, a 24-hour gym, and a restaurant are all featured at this smoke-free hotel. Traveling on business? Take advantage of the business center, ...
The property was excellently maintained!

Reviewed on Apr 2, 2026

Opens in a new windowGrand Bohemian Lodge Greenville, Autograph Collection
Drury Inn & Suites Greenville

Drury Inn & Suites Greenville

3 out of 5
10 Carolina Point Pkwy Greenville SC
Fully refundableReserve now, pay when you stay
$119 nightly
The price is $131 total per night from Apr 12 to Apr 13
$131 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features an outdoor pool and an indoor pool. Traveling on business? Take advantage of the business center and free WiFi in public areas. Enjoy the ...
Hot tub was nice and beds were comfy

Reviewed on Apr 6, 2026

Opens in a new windowDrury Inn & Suites Greenville
Embassy Suites Greenville Golf Resort & Conference Center

Embassy Suites Greenville Golf Resort & Conference Center

3.5 out of 5
670 Verdae Blvd Greenville SC
$134 nightly
The price is $148 total per night from Apr 12 to Apr 13
$148 total
Apr 12 - Apr 13
Total with taxes and fees
A golf course, a 24-hour gym, and a restaurant are all featured at this resort. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Clean and nice.

Reviewed on Apr 5, 2026

Opens in a new windowEmbassy Suites Greenville Golf Resort & Conference Center
Hyatt Regency Greenville

Hyatt Regency Greenville

3.5 out of 5
220 N Main St Greenville SC
Fully refundableReserve now, pay when you stay
$162 nightly
The price is $178 total per night from May 3 to May 4
$178 total
May 3 - May 4
Total with taxes and fees
This smoke-free hotel features 2 restaurants, a bar/lounge, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Property was clean for the most part. Lot of issues with people on the floors partying, but I think it was a special group that was in town for something. Had to call the front desk for security as we couldn’t sleep it almost 1 AM. But the staff was amazing. That’s for sure.

Reviewed on Mar 30, 2026

Opens in a new windowHyatt Regency Greenville
Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

Crowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG

3.5 out of 5
851 Congaree Rd Greenville SC
Fully refundable
$105 nightly
The price is $116 total per night from Apr 12 to Apr 13
$116 total
Apr 12 - Apr 13
Total with taxes and fees
This smoke-free hotel includes 2 restaurants, an indoor pool, and a 24-hour gym. Traveling on business? Take advantage of the 24-hour business center, free WiFi ...
Staff was wonderful Bresyln she was very helpful from the first call I made to check in early she made sure I had everything I needed and the room in the perfect spot!! Thanks so much we will definitely will be back!!

Reviewed on Apr 5, 2026

Opens in a new windowCrowne Plaza Hotel Greenville-I-385-Roper Mtn Rd by IHG
Hilton Greenville

Hilton Greenville

3.5 out of 5
45 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Apr 12 to Apr 13
$109 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the 18 conference rooms, free WiFi in public areas, ...
Very clean

Reviewed on Apr 6, 2026

Opens in a new windowHilton Greenville
Best Western Plus Clemson Hotel & Conference Center

Best Western Plus Clemson Hotel & Conference Center

2.5 out of 5
1310 Tiger Blvd Clemson SC
Fully refundableReserve now, pay when you stay
$101 nightly
The price is $112 total per night from Apr 12 to Apr 13
$112 total
Apr 12 - Apr 13
Total with taxes and fees
This hotel features a 24-hour gym and a seasonal outdoor pool. Traveling on business? Take advantage of the 24-hour business center and free WiFi in public areas. ...
Elevator was gross. Bathroom was not cleaned

Reviewed on Apr 5, 2026

Opens in a new windowBest Western Plus Clemson Hotel & Conference Center
Hyatt Place Greenville/Haywood

Hyatt Place Greenville/Haywood

3 out of 5
40 W Orchard Park Dr Greenville SC
Fully refundableReserve now, pay when you stay
$99 nightly
The price is $109 total per night from Apr 17 to Apr 18
$109 total
Apr 17 - Apr 18
Total with taxes and fees
This hotel features a restaurant, a 24-hour gym, and a bar/lounge. Traveling on business? Take advantage of the business center and free WiFi in public areas. ...
It was good

Reviewed on Apr 5, 2026

Opens in a new windowHyatt Place Greenville/Haywood
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Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Cheap Upstate South Carolina hotels

Baymont by Wyndham Anderson Clemson

Baymont by Wyndham Anderson Clemson

128 Interstate Blvd Anderson SC
$72 nightly
The price is $80 total per night from Apr 13 to Apr 14
$80 total
Apr 13 - Apr 14
Total with taxes and fees
7/10 Good! (872 reviews)
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Upstate South Carolina hotel reviews by fellow wanderers

Hilton Greenville

Hilton Greenville

5 out of 5
Posted 3 hours ago
Travelocity Verified Review
"Very clean "
A verified traveler stayed at Hilton Greenville
Hilton Greenville

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